ADPGK antisense RNA 1 (ADPGK-AS1) promotes GC development through upregulation of LSD2 by sponging miR-3196, making it a potential new prognostic biomarker and therapeutic target for GC patients, and ADPGK-AS1 is dramatically overexpressed in GC cell lines compared to normal gastric epithelial cell lines [11]. This evidence concerns the gene ADPGK-AS1 and gastric cancer.