However, in the present study, we found that, similar to IL-4 and IL-13 [17], the TSG6 mRNA and/or protein levels remained the same in PLF, peritoneal macrophages, and spleen after zymosan injection, indicating that TSG6 is not involved in the STAT6 pathway during zymosan-induced peritonitis. The gene discussed is IL13; the disease is peritonitis.