Mutations in other genes causative for ALS/FTD were excluded (i.e., C9orf72, MAPT, VCP, TARDBP, FUS, SOD1, TBK1, ATXN2, UBQLN2, SQSTM1 and TREM2) [7]. The gene discussed is MAPT; the disease is amyotrophic lateral sclerosis.