Acute attacks of MS are treated with high doses of corticosteroids, but the overall prognosis can be changed only by early treatment with disease-modifying drugs that now includes a number of options: interferon beta, glatiramer acetate, teriflunomide, dimethyl fumarate, fingolimod, cladribine, natalizumab, ocrelizumab, alemtuzumab, ofatumumab, siponimod, and non-specific immunosuppressive drugs. This evidence concerns the gene IFNB1 and myeloid sarcoma.