Consistent with our results, previous research has reported that high LC3, PINK1 and p62 protein levels are associated with triple-negative BC (TNBC) patients and with poor response to chemotherapy, similar results have also been found in colorectal cancer, gastric, malignant melanoma, and esophageal cancer [54,55,56,57,58,59,60,61]. The gene discussed is SQSTM1; the disease is esophageal cancer.