RSV was also described to decrease the transcription levels of all the evaluated DNMTs, namely DNMT1, DNMT3a, and DNMT3b in addition to the reduction in the protein levels of DNMT1, HDAC1, and MeCP2 in human breast carcinoma cell lines MCF7 and MDA MB 231 [162]. This evidence concerns the gene HDAC1 and breast carcinoma.