GLI2 and breast cancer: In the human breast epithelial MCF10A cell line, RSV inhibited the cell growth via various mechanisms, including the decrease in DNA methylation in promoters of potential tumor suppressor genes, but its increase in regulatory regions of potential oncogenes, increased methylation levels of CpG sites in MAML2 and GLI2 enhancers compared to levels present in normal cells and decreased methylation of CpG sites in SEMA3A enhancer and the CpG island of GLI2 leading to altered DNA methylation patterns in breast cancer cells.