Recently, Weng et al. [284] revealed that incubation of lung cancer and pre-malignant oral cell lines with this acid for seven days induces changes in the methylome of cells, clears DNMT1 and reduces the expression level of this cytoplasmic enzyme, which could suggest that treatment with gallic acid has a strong inhibitory effect via decreasing protein stability and nuclear import. This evidence concerns the gene DNMT1 and lung cancer.