In the study reported by Kala et al. [314] on the breast cancer cell lines (MDA-MB-157, HCC1806, and MCF10A), PTS and RSV have inhibited synergistically TNBC growth, downregulated the SIRT1 and the DNMT enzymes with no significant effects on DNMT enzyme expression in MCF10A control cells. The gene discussed is SIRT1; the disease is breast carcinoma.