Enhanced the mRNA and protein levels of ras-association domain family protein 1A (RASSF1A), 1 hypermethylation-silenced TSG, and decreased its promoter methylation in breast cancer cellsDecreased the DNA methylation activity of nuclear extractDownregulated the mRNA and protein levels of DNMT1 in MCF-7 cells. The gene discussed is RASSF1; the disease is breast carcinoma.