-Enhanced the BRCA1 (breast cancer type 1 susceptibility protein) expression levels in TNBC (triple-negative breast cancer)-Inhibited the cell survival of TNBC cell lines-Enhanced the BRCA1 expression-Induced the histone acetylation of BRCA1 promoter-Inhibited the migratory ability of TNBC cell lines and regulated genes involved in tumor migration-Downregulated the T47D cells in BRCA1⇒ Quercetin may induce anticancer activity against TNBC cells by modulating tumor suppressor genes. Here, BRCA1 is linked to triple-negative breast carcinoma.