-Inhibited the growth of MCF-7 and MDA-MB-231 cells in a dose-and time-dependent manner-Increased the levels of the miR-146a expression in MCF-7 and MDA-MB-231 in a dose-dependent manner-Stimulated the expression of bax and caspase-3-Inhibited the expression of EGFR (epidermal growth factor receptor) via upregulation of the miR-146a expression-Inhibited the tumor growth in nude mouse⇒ Quercetin inhibits cell proliferation in human breast cancer cells by upregulating miR-146a expression, and downregulating the expression of EGFR. Here, CASP3 is linked to breast cancer.