SERPINE2 and hepatocellular carcinoma: This reduces YTHDF2 expression in HCC cells and therefore decreases the degradation of m6A-containing IL-11 and serpin family E member 2 (SERPINE2) mRNAs which are crucial factors in inflammation-mediated malignancy and vascular remodeling, and therefore enhances inflammation, angiogenesis, and metastasis [65].