Studies on human postmortem brain tissue have shown the colocalization of the microtubule-associated protein 1A/1B-light chain 3 (LC3), a marker for autophagic vacuoles, with accumulated α-syn and LBs in the SN of PD patients [42] and in vulnerable brain regions in DLB patients [43]. This evidence concerns the gene MAP1LC3A and Lewy body dementia.