Representative examples for p-ERK staining of melanomas collected 4 h after treatment are shown on Figure 1D. We also performed immunohistochemistry for the proliferation marker Ki-67 in YUMM1.7 melanoma xenografts collected 24 h after single treatment with BRAFi, MEKi, or combined BRAFi/MEKi (combo). Here, MKI67 is linked to melanoma.