TARDBP and amyotrophic lateral sclerosis: Both direct restoration of STMN2 through lentiviral delivery of STMN2 gene without the cryptic polyadenylation site in the corresponding RNA [8] and JNK1 inhibition [15] rescue axonal phenotypes in TARDBP-depleted neurons, suggesting that reduction in STMN2 is sufficient to impair axonal function in ALS.