Levels of circulating cytokines are abnormal in ALS patients, with higher levels of TNF-α, IL-1 β, IL-2, IL-8, IL-12p70, IL-4, IL-5, IL-10, and IL-13, and lower levels of INF-γ when compared to healthy controls [10]. Here, CXCL8 is linked to amyotrophic lateral sclerosis.