SRC and neuroblastoma: After the demonstration by western blot analyses of the constitutive expression of both c-Src and its phosphorylated form (see Figure S1 in the Supplementary Materials), both representing the pharmacological targets of Si306, the cytotoxic effects of Si306, either free or encapsulated in untargeted or GD2-targeted liposomes, were tested against HTLA-230, IMR-32 and SH-SY5Y NB cell lines.