In line with this, the bioinformatic analysis of the TCGA database revealed that the high expression of the genes coding IL6, IL10, IL12, ICAM-1, ICAM-3, PECAM-1, and CD40L in tissues of patients with metastatic melanoma correlates with the better survival prognosis (Figure 8). The gene discussed is PECAM1; the disease is metastatic melanoma.