LEP and metabolic dysfunction-associated steatotic liver disease: Thus, adipokines, when imbalanced, have the ability to stimulate not only a pro-inflammatory state by secreting multiple proteins, such as adiponectin or leptin, as well as cytokines with multiple biological activities, but also an insulin-resistant state, with both contributing to the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and its future progression to non-alcoholic steatohepatitis [23,24,25].