KDR and hepatocellular carcinoma: This was in agreement with the absence of ABCB1 expression in parental HCC 1806 cells, as was shown in Figure 1A. In contrast, PD 173074, a well-known FGFR1 and VEGFR2 inhibitor do not have an impact on the efflux of Сalcein AM from the naive and resistant TNBC cells, as well (Figure 4A,B, respectively), thereby illustrating the novel (“off-target”) effect of BGJ 398 on ABCB1 transporter in TNBC cells.