MAPT and multiple system atrophy: The presence of tau-positive granules not co-localized with αSyn-positive GCIs in the oligodendroglia, with a more common expression of 4-repeat (R) than 3-R tau, and related to the severity of neurodegeneration in MSA, suggested that tau may be related to a neurodegenerative pathway different from that induced by αSyn, which is particularly associated with memory impairment in MSA [132].