CD8A and hepatocellular carcinoma: Bacteroides, Veillonellaceae, and Ruminococcus are correlated with proinflammatory markers, inflammation and fibrosis markers in NAFLD patients [83,84], Bacteroides xylanisolvens and Veillonella parvula have shown a significant positive correlation with Treg cells, and Ruminococcus gnavus has a positive correlation with Treg cells but a significant negative correlation with cytotoxic CD8+ T cells, suggesting a gut microbiota immunomodulatory response in NAFLD-HCC patients.