At the functional level, Gorman et al. recently studied the effects on viral sensitivity and autoimmune pathogenesis of rs1990760, an erroneous variant of IFIH1 that is associated with multiple autoimmune diseases (type 1 diabetes mellitus, systemic lupus erythematosus, vitiligo, autoimmune thyroid disease, etc.)[66]. Here, IFIH1 is linked to systemic lupus erythematosus.