At the functional level, Gorman et al. recently studied the effects on viral sensitivity and autoimmune pathogenesis of rs1990760, an erroneous variant of IFIH1 that is associated with multiple autoimmune diseases (type 1 diabetes mellitus, systemic lupus erythematosus, vitiligo, autoimmune thyroid disease, etc.)[66]. This evidence concerns the gene IFIH1 and autoimmune thyroid disease.