The study shows that in both groups, control and CoQ10, CD4+ count was significantly increased, without changes in markers of liver and kidney function, although the study does not demonstrate the efficacy of CoQ10 on T cell count, it is worth mentioning that conventional treatment could be responsible for the results obtained, however, in these patients with HIV infection it has been described that their CoQ10 levels endogenous are significantly decreased, so supplementation with CoQ10 helps to restore this deficiency. The gene discussed is CD4; the disease is HIV infectious disease.