Several studies show that t(11;14) leading to CCND1 dysregulation are significantly more frequent in pPCL than in MM, reaching percentages as high as 45–70% in some series [8,17,18,21,22,23,24,27,40,41]; also noteworthy is the high proportion of t(14;16) detected in pPCL compared with MM (13–25% vs. 1–5%, respectively), which is supported by five studies [18,21,23,36,41]. Here, CCND1 is linked to Miyoshi myopathy.