After gating on CD34+/CD117+ cells (using MFI values of 1000 as cutoff), differentiation towards the B-cell (CD19+), megakaryocytic/erythroid (CD36+/CD64−), erythroid (CD105+), monocytic (CD64+), neutrophilic (CD15+) and megakaryocytic (CD42a.CD61+) lineage was defined in both the AMKL and non-AMKL patients. The gene discussed is ITGB3; the disease is acute megakaryoblastic leukemia.