To investigate INK4 protein levels in AML, we analysed microarray data from healthy human bone marrow (BM) and CDK6-dependent AML subtypes harbouring RUNX1-RUNX1T1 t(8;21) fusion or KMT2A rearrangements t(11q23) (KMT2Ar) with a focus on KMT2A-MLLT3 t(9;11). Here, CDK6 is linked to acute myeloid leukemia.