Primary tumors with any BRAF mutation developing lymph node metastasis had also significantly lower miR-125b, miR-200c and miR-205 (p-value 0.0499, 0.0268 and 0.017, respectively) compared to tumors not presenting lymph node metastasis (Figure 4C). The gene discussed is BRAF; the disease is metastatic malignant neoplasm in the lymph nodes.