Thus, to validate these results in a PDA cellular model and demonstrate that c-MYC requires BPTF to regulate its chromatin recruitment as well as the transcription of ABC-transporters, we analyzed c-MYC chromatin recruitment by ChIP-qPCR in T3M4 controls or BPTF-silenced on ABCC1. The gene discussed is MYC; the disease is Patent ductus arteriosus.