RWPE-1 and prostate cancer (DU-145, PC-3 and ARCaP-M) cells and LT-2 and pancreatic cancer (MIA PaCa-2, AsPC-1 and PANC-1) cells were transfected with pGADD, pPEG, pGAPE, pT-GADD, pT-GADD1-1, pT-GADD2-2 and pT-GADD-2 along with PRL-TK for 48 h. The gene discussed is PRL; the disease is pancreatic neoplasm.