PPP1R15A and cancer: To determine if a single mutation or both mutations (bp −260 or bp +159) in the full-length GADD34-Prom (pT-GADD, 1558 bp) could confer cancer selectivity, we developed total pT-GADD constructs with a single mutation at G-A, pT-GADD1-1-Luc or C-T, pT-GADD2-2-Luc, and with both the mutations, pT-GADD2-Luc (sequence information, Supplementary Data).