Furthermore, the HD of Cdkn2a/2b was detected in iron-saccharate-induced sarcomatoid mesothelioma (SM) (4/5) and epithelioid mesothelioma (EM) (0/6) in BN/F344 F1 hybrid rats [91], and EM (1/5) was observed in male Wistar rats [92]. This evidence concerns the gene CDKN2A and erythema multiforme.