18F/11C-Choline is a well-established positron emission tomography (PET) radiopharmaceutical, approved by the Food and Drug Administration (FDA) in 2012 for PCa patients with biochemical recurrence, but with suboptimal detection rate especially in prostate/prostatectomy bed at very low PSA values [5,6]. The gene discussed is KLK3; the disease is posterior cortical atrophy.