Many studies have found that the mitophagy-related molecules phosphatase and tensin (PTEN)-induced kinase 1 (PINK1), parkin, Bcl-2/adenovirus E1B 19 kDa interacting protein 3 (BNIP3), FK506-binding protein 8 (FKBP8) and FUN14 domain-containing protein 1 (FUNDC1) promote tumor formation and can be used as therapeutic targets in a variety of malignancies [493,494,495,496]. This evidence concerns the gene FUNDC1 and neoplasm.