The authors also analysed SETD7 levels in 20 glioma and neighbouring normal tissues, with lower mRNA in glioma, while Kaplan–Meier curves plotted from clinical data showed that high expression of SETD7 was associated with better overall survival, suggesting SETD7 has a tumour-suppressor role in glioma [58]. This evidence concerns the gene SETD7 and central nervous system cancer.