Because NT5DC2 is a cytoplasmatic protein, which can be found not only in NSCLC but also in leiomyosarcoma [21], colorectal cancer [20] and hepatocellular carcinoma [23], therapeutic interactions are conceivable for multiple entities, and its interaction with p53 makes it a valuable target for further investigation. The gene discussed is TP53; the disease is leiomyosarcoma.