However, with respect to TP53 mutations and p53 isoforms, available TCGA-data on TP53 mutations in adeno-carcinoma patients (e.g., https://portal.gdc.cancer.gov/projects/TCGA-LUAD, accessed on 3 March 2022) cannot be matched to the small number of TCGA-derived gene-expression patients, as our ‘kmplot.com’ source does not allow for matching but are urgently needed for a better understanding of this complex interaction. This evidence concerns the gene TP53 and adenocarcinoma.