KRAS and colorectal neoplasm: For example, activating mutations in the Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) or V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) oncogenes confer proliferative characteristics and are found in 30% or 15% of sporadic colorectal tumours, respectively [3,4,5].