Enrichment of CD8+ cytotoxic CAR-T cells and less-differentiated stem cell-like memory T cells was observed without harming the proliferation, cytokine release, and cytotoxicity of anti-CAIX CAR T cells, proving the synergistic effects of sunitinib with anti-CAIX CAR T cells against RCC [53]. Here, CA9 is linked to renal cell adenocarcinoma.