IL2 and vasculitis: In another study using the same mouse model, the use of a complex consisting of IL-2 and anti-IL2 monoclonal antibody (JES6-1) demonstrated attenuation of renal glomerular and tubular injury, vasculitis and renal depositions of C3 and anti-dsDNA antibodies, coupled with improvement of peripheral disease activity including elevation of serum complements and reduction in anti-dsDNA level by sustained expansion of CD4+CD25+FoxP3+ Treg [58].