Thus, Hsp90 is perhaps one of the most widely studied heat shock proteins [66] as it is at the epicenter of human diseases, including neurodegenerative diseases, pulmonary/respiratory diseases (pulmonary arterial hypertension, acute pulmonary fibrosis, asthma) and different types of cancer [12,13,67,68,69,70]. This evidence concerns the gene HSP90AB1 and neurodegenerative disease.