Similarly, Ivancic et al. revealed that CRC blood containing LRG1, EGFR, ITIH4, HPX, and SOD3 showed 89% specificity and 70% sensitivity in detecting CRC and that the proteins GC, CD44, CRP, and ITIH3 can potentially distinguish CRC according to their stages [62]. Here, ITIH3 is linked to colorectal carcinoma.