In addition, numerous studies have reported the unexpected expression of Vav1 in a variety of human cancers of various histological origin including the hematopoietic system [7,8,9], as well as solid tumors such as neuroblastoma [10], lung [11], pancreas [12], breast [13,14], ovarian [15], prostate [16], esophageal [17], and brain tumors [18]. The gene discussed is VAV1; the disease is cancer.