C9orf72 and amyotrophic lateral sclerosis: Considering the ALS–FTD group, significantly lower values were found in the sporadic group in lobule VIIa-Crus I and the deep nuclei, while C9orf72 expansion carriers showed significantly lower values in lobule I–IV, VIIa-Crus II and dentate nuclei compared to controls (Table 2, Figure 2).