Considering the ALS–FTD group, significantly lower values were found in the sporadic group in lobule VIIa-Crus I and the deep nuclei, while C9orf72 expansion carriers showed significantly lower values in lobule I–IV, VIIa-Crus II and dentate nuclei compared to controls (Table 2, Figure 2). The gene discussed is C9orf72; the disease is frontotemporal dementia.