Notably, L. minor lung protection markedly decreased in the IL-1β levels (by 38.82 ± 5.41, p < 0.0003, t-test) and TNF-α levels (by 232.87 ± 35.09, p < 0.0062, t-test), compared to BLM-induced fibrosis group, on the course 33 days, respectively. Here, IL1B is linked to fibrosis.