NFE2L2 and coronary artery disorder: Additionally, in a study that included 2374 Thai subjects with a high risk of CAD and without CAD, the association between Nrf2 rs6721961 TT, the severity of coronary atherosclerosis, and CAD was demonstrated in the entire population, whereas the association with the NQO1 rs1800566 CC genotype was established only in female [108].