Similar to our previously reported findings [19], aged vehicle-treated mice demonstrated persistent lung fibrosis at 6 weeks post-injury, as demonstrated by histopathology (Figure 4A; top panels), lung collagen deposition (Figure 4A; bottom panels), elevated fibronectin (Figure 4B,C) and collagen-1α (Figure 4D,E) expression levels, and elevated lung hydroxyproline levels (Figure 4F). The gene discussed is FN1; the disease is pulmonary fibrosis.