GAS5 and Sepsis: Recent studies disclose that lnc‐GAS5 inhibits the differentiation of T cells into Th17 cells, macrophage M1 polarization while promotes macrophage M2 polarization, and restrains the inflammation as well as sepsis‐induced organ injury in multi‐complex diseases, which implies that it might be engaged in the pathogenesis of sepsis.15, 16, 17, 18, 19, 20, 21 Nevertheless, the clinical involvement of lnc‐GAS5 in sepsis remains unclear.