For example, gja3/Cx46 has only been examined in the heart (Chi et al. 2008, 2010), yet, in our dataset, we find robust gja3/Cx46 expression in both heart and lens clusters, which suggests an enticing link to human GJA3/CX46, in which mutations are associated with cataracts (Mackay et al. 1999; Burdon et al. 2004; Yao et al. 2011). The gene discussed is GJA3; the disease is cataract.