Also, while our phenotyping data demonstrates that the GSE that develops in JH-/- (and previously in CD19-/-) mice is a T-cell-dependent phenomenon, we have not demonstrated that this enteropathy is an antigen-specific response to gluten peptides (though the recent findings by Petersen et al. demonstrate that this may not be a requirement for the initiation of gluten sensitivity [51]). The gene discussed is CD19; the disease is Abnormal intestine morphology.