On the other hand, indole-3-acetic acid has also been positively associated with the activation of stem cell factor (SCF), which plays a role in tissue repair, hematopoiesis and cell proliferation [104] and with anti-inflammatory and anti-oxidant activity on lipopolysaccharide stimulated macrophages [105], albeit at concentrations exceeding more than 30 times those observed in uremia. This evidence concerns the gene KITLG and uremia.