EGF and hepatocellular carcinoma: In the 1990s, researchers reported the use of ITs of TCS with Hepama-1 (human hepatoma) [89], CMU15A (Lung cancer antigen) [118], anti-p75-anti-mouse IgG (p75: nerve growth factor) [117], Ng76 (Melanoma) [119], and EGF (hepatocellular carcinoma) [120,121,122] (Table 2).