In the MAB groups, post hoc Bonferroni tests showed that the anterior cingulate, dorsolateral prefrontal cortex (DLPFC), orbitofrontal cortex (OFC), parietal and ventricular system (VS) regions had significantly higher SUV in PD than in HC, and the anterior cingulate, anterior frontal, DLPFC, dentate nucleus, hypothalamus, medulla, OFC, posterior cingulate, parietal, pons, temporal and cerebellum regions had significantly higher SUV in lrrk2-UC than in HC. This evidence concerns the gene LRRK2 and Parkinson disease.