It was observed that changes in the expression levels of the CXCL10, ATP10A, and TLR6, as well as the DOCK9, EPHA4, and NPC2 genes from peripheral blood samples, incubated with PPD, significantly differed in patients with active TB, people with an LTBI, and healthy individuals from England, Africa, and Brazil [141,142]. This evidence concerns the gene NPC2 and tuberculosis.