Dawei Liu et al., concluded that miR-328-3p in the apoptotic bodies of mesenchymal stem cells inhibits Axin1, it activates the wnt/β-catenin pathway and promotes osteogenesis and inhibits osteoporosis, which implies the potential use of apoptotic bodies in the treatment of osteoporosis [21]. This evidence concerns the gene AXIN1 and osteoporosis.