IL18 and fatty liver disease: Specifically, inflammasomes, that are quite distinct in that they form a high molecular weight caspase-1 activating complex, control the maturation and secretion of Interleukin 1β (IL-1β) and Interleukin 18 (IL-18); these cytokines play an essential role in the inflammatory response involved in the development and pathogenesis of fatty liver diseases (Figure 2) [25,26,27,28,29,30,31,32].