ESM1 and type 2 diabetes mellitus: Of the 13 prognostic and diagnostic proteins, three were lower in T2D: Adiponectin (1885 ± 100 vs. 3319 ± 304 RFU, T2D vs. control, p < 0.0001), Endocan (894 ± 41 vs. 1061 ± 64 RFU, T2D vs. control, p < 0.05) and Mast/stem cell growth factor receptor-Kit (KIT) (14,690 ± 905 vs. 18,863 ± 1104 RFU, T2D vs. control, p < 0.01) (Figure 1A–C).