Previous studies have shown that the cholinergic anti-inflammatory pathway regulated by α7 nAChR is a key pathway for the treatment of pneumonia and that α7 nAChR can affect the proliferation, angiogenesis, metastasis, and apoptosis of lung cancer cells, gastric cancer cells, colon cancer cells, and other malignant tumor cells [15,16,17]. The gene discussed is CHRNA7; the disease is colonic neoplasm.